Biomimetic Microgels with Controllable Deformability Improve Healing Outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201800042
Abstract: Platelets mediate hemostasis by aggregating and binding to fibrin to promote clotting. Over time, platelets contract the fibrin network to induce clot retraction, which contributes to wound healing outcomes by increasing clot stability and improving… read more here.
Keywords: clot; clot retraction; degrees shell; healing outcomes ... See more keywords
Engineering the Deformability of Albumin-Stabilized Emulsions for Lymph-Node Vaccine Delivery.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced materials"
DOI: 10.1002/adma.202100106
Abstract: A major challenge in vaccine delivery is to achieve robust lymph-node (LN) accumulation, which can capitalize on concentrated immunocytes and cytokines in LNs to stimulate the onset and persistence of adaptive immune responses. Previous attempts… read more here.
Keywords: vaccine delivery; delivery; deformability albumin; deformability ... See more keywords
Integrated automated particle tracking microfluidic enables high‐throughput cell deformability cytometry for red cell disorders
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25345
Abstract: Investigating individual red blood cells (RBCs) is critical to understanding hematologic diseases, as pathology often originates at the single‐cell level. Many RBC disorders manifest in altered biophysical properties, such as deformability of RBCs. Due to… read more here.
Keywords: cell deformability; deformability; rbc; cell ... See more keywords
Optomechanical measurement of the role of lamins in whole cell deformability.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600198
Abstract: There is mounting evidence that the nuclear envelope, and particularly the lamina, plays a critical role in the mechanical and regulation properties of the cell and changes to the lamina can have implications for the… read more here.
Keywords: whole cell; optical stretcher; role; deformability ... See more keywords
Signaling mechanisms in red blood cells: A view through the protein phosphorylation and deformability.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30958
Abstract: Intracellular signaling mechanisms in red blood cells (RBCs) involve various protein kinases and phosphatases and enable rapid adaptive responses to hypoxia, metabolic requirements, oxidative stress, or shear stress by regulating the physiological properties of the… read more here.
Keywords: signaling mechanisms; red blood; protein phosphorylation; deformability ... See more keywords
Deformability of ascending thoracic aorta aneurysms assessed using ultrafast ultrasound and a principal strain estimator: In vitro evaluation and in vivo feasibility.
Sign Up to like & getrecommendations! Published in 2022 at "Medical physics"
DOI: 10.1002/mp.15464
Abstract: BACKGROUND Noninvasive vascular strain imaging under conventional line-by-line scanning has a low frame rate and lateral resolution, and depends on the coordinate system. It is thus affected by high deformations due to image decorrelation between… read more here.
Keywords: strain estimator; principal strain; strain; deformability ... See more keywords
Microfluidic Impedance-Deformability Cytometry for Label-Free Single Neutrophil Mechanophenotyping.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202104822
Abstract: The intrinsic biophysical states of neutrophils are associated with immune dysfunctions in diseases. While advanced image-based biophysical flow cytometers can probe cell deformability at high throughput, it is nontrivial to couple different sensing modalities (e.g.,… read more here.
Keywords: label free; cell; microfluidic impedance; deformability ... See more keywords
PillarX: A Microfluidic Device to Profile Circulating Tumor Cell Clusters Based on Geometry, Deformability, and Epithelial State.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202106097
Abstract: Circulating tumor cell (CTC) clusters are associated with increased metastatic potential and worse patient prognosis, but are rare, difficult to count, and poorly characterized biophysically. The PillarX device described here is a bimodular microfluidic device… read more here.
Keywords: circulating tumor; geometry; deformability; tumor cell ... See more keywords
Improved Erythrocyte Deformability Induced by Sodium-Glucose Cotransporter 2 Inhibitors in Type 2 Diabetic Patients
Sign Up to like & getrecommendations! Published in 2020 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-020-07067-w
Abstract: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are antidiabetic drugs that improve cardiovascular outcomes. Hemoglobin and hematocrit values increase after SGLT-2 inhibitor administration. Although these factors increase blood viscosity and the risk of cardiovascular disease, SGLT-2 inhibitors… read more here.
Keywords: sglt inhibitor; inhibitor; erythrocyte deformability; deformability ... See more keywords
Deformability of Oxide Inclusions in Tire Cord Steels
Sign Up to like & getrecommendations! Published in 2017 at "Metallurgical and Materials Transactions B"
DOI: 10.1007/s11663-017-1134-2
Abstract: The deformation of oxide inclusions in tire cord steels during hot rolling was analyzed, and the factors influencing their deformability at high and low temperatures were evaluated and discussed. The aspect ratio of oxide inclusions… read more here.
Keywords: tire cord; inclusions tire; oxide inclusions; cord steels ... See more keywords
Influence of MAX-Phase Deformability on Coating Formation by Cold Spraying
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thermal Spray Technology"
DOI: 10.1007/s11666-020-01110-w
Abstract: As solid-state deposition technique avoiding oxidation, cold gas spraying is capable of retaining feedstock material properties in the coatings, but typically fails to build up coatings of brittle materials. Ceramic MAX phases show partial deformability… read more here.
Keywords: phase; max phase; cold spraying; deformability ... See more keywords