Acarbose potentially binds to the type I peptide deformylase catalytic site and inhibits bacterial growth: An in silico and in vitro study.
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DOI: 10.2174/1381612828666220922100556
Abstract: BACKGROUND In bacteria, peptide deformylase (PDF), a metalloenzyme, removes N-formyl methionine from a nascent protein, which is a critical step in the protein maturation process. The enzyme is ubiquitously present in bacteria and possesses therapeutic… read more here.
Keywords: peptide deformylase; deformylase catalytic; catalytic site; site ... See more keywords