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Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202104888
Abstract: Intervertebral disc degeneration (IDD) results from the dysfunction of nucleus pulposus (NP) cells and the exhaustion of NP progenitors (ProNPs). The cellular applications of NP cells during IDD are currently limited due to the lack…
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Keywords:
pronps;
degeneration;
nucleus pulposus;
intervertebral disc ... See more keywords
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Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.812
Abstract: In chronic inflammatory demyelinating polyneuropathy (CIDP), exclusion of secondary axonal degeneration is challenging with conventional methods such as nerve conduction study (NCS), needle electromyography, and nerve biopsy. Increased echo intensity (EI) and decreased muscle thickness…
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Keywords:
inflammatory demyelinating;
muscle;
chronic inflammatory;
axonal degeneration ... See more keywords
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Published in 2017 at "Clinical Anatomy"
DOI: 10.1002/ca.22866
Abstract: Hypertrophic olivary degeneration (HOD) following a lesion of the dentato–rubro–olivary pathway (DROP) is a well‐known imaging finding and has extensively been described in the recent literature. We reviewed our patients with HOD as a result…
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Keywords:
olivary degeneration;
degeneration;
dentato rubro;
rubro olivary ... See more keywords
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Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11959
Abstract: Amyloid‐β (Aβ) is thought to be a critical pathologic factor of retinal pigment epithelium (RPE) degeneration in age‐related macular degeneration (AMD). Aβ induces inflammatory responses in RPE cells and recent studies demonstrate the N6‐methyladenosine (m6A)…
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Keywords:
degeneration;
pka;
rpe degeneration;
retinal pigment ... See more keywords
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Published in 2023 at "International journal for numerical methods in biomedical engineering"
DOI: 10.1002/cnm.3704
Abstract: Transcatheter aortic valve implantation (TAVI) is a minimally invasive intervention for the treatment of severe aortic valve stenosis. The main cause of failure is the structural deterioration of the implanted prosthetic leaflets, possibly inducing a…
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Keywords:
aortic valve;
degeneration;
valve implantation;
transcatheter aortic ... See more keywords
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Published in 2020 at "Developmental Dynamics"
DOI: 10.1002/dvdy.217
Abstract: Chronic low back and neck pain are associated with intervertebral disc degeneration and are major contributors to the global burden of disability. New evidence now suggests that disc degeneration comprises a spectrum of subphenotypes influenced…
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Keywords:
based therapies;
degeneration;
cell based;
intervertebral disc ... See more keywords
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Published in 2017 at "Glia"
DOI: 10.1002/glia.23165
Abstract: A striking aspect of tissue regeneration is its uneven distribution among different animal classes, both in terms of modalities and efficiency. The retina does not escape the rule, exhibiting extraordinary self‐repair properties in anamniote species…
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Keywords:
glial cell;
cell reactivation;
ller glial;
cell ... See more keywords
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Published in 2022 at "Glia"
DOI: 10.1002/glia.24309
Abstract: Following peripheral nerve injury (PNI), Wallerian degeneration (WD) in the distal stump can generate a microenvironment favorable for nerve regeneration. Brief low‐frequency electrical stimulation (ES) is an effective treatment for PNI, but the mechanism underlying…
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Keywords:
nerve injury;
regeneration;
degeneration;
nerve regeneration ... See more keywords
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Published in 2019 at "Human Brain Mapping"
DOI: 10.1002/hbm.24695
Abstract: Trans‐neuronal propagation of mutant huntingtin protein contributes to the organised spread of cortico‐striatal degeneration and disconnection in Huntington's disease (HD). We investigated whether the network diffusion model, which models transneuronal spread as diffusion of pathological…
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Keywords:
degeneration disconnection;
huntington disease;
disconnection;
brain ... See more keywords
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Published in 2021 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30611
Abstract: Mechanisms involved in the development of intervertebral disc (IVD) degeneration are only partially known, thus making the implementation of effective therapies very difficult. In this study, we investigated P2X7 purinergic receptor (P2X7R), NLRP3 inflammasome, and…
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Keywords:
p2x7r nlrp3;
p2x7r;
intervertebral disc;
purinergic receptor ... See more keywords
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Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30757
Abstract: Yes‐associated protein (YAP) is a major component of the Hippo pathway involved in development, growth, repair and homeostasis. Nonsense YAP1 mutations in humans result in autosomal dominant coloboma. Here, we generated a conditional knockout mouse…
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Keywords:
degeneration;
retinal degeneration;
onset retinal;
hippo ... See more keywords