Network spread determines severity of degeneration and disconnection in Huntington's disease
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DOI: 10.1002/hbm.24695
Abstract: Trans‐neuronal propagation of mutant huntingtin protein contributes to the organised spread of cortico‐striatal degeneration and disconnection in Huntington's disease (HD). We investigated whether the network diffusion model, which models transneuronal spread as diffusion of pathological… read more here.
Keywords: degeneration disconnection; huntington disease; disconnection; brain ... See more keywords