The NAD+ precursor NMN activates dSarm to trigger axon degeneration in Drosophila
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DOI: 10.1101/2022.01.30.478002
Abstract: Axon degeneration contributes to the disruption of neuronal circuit function in diseased and injured nervous systems. Severed axons degenerate following the activation of an evolutionarily conserved signaling pathway, which culminates in the activation of SARM1… read more here.
Keywords: nad precursor; degeneration; axon degeneration; nmn ... See more keywords