An intervertebral disc whole organ culture system to investigate proinflammatory and degenerative disc disease condition
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2636
Abstract: The aim of this study was to compare the effect of different disease initiators of degenerative disc disease (DDD) within an intervertebral disc (IVD) organ culture system and to understand the interplay between inflammation and… read more here.
Keywords: proinflammatory; degenerative disc; condition; disease ... See more keywords
Degenerative Disc Disease: What's in a Name?
Sign Up to like & getrecommendations! Published in 2019 at "Spine"
DOI: 10.1097/brs.0000000000003103
Abstract: STUDY DESIGN A systematic search and review OBJECTIVE.: To investigate the term, degenerative disc disease, to elucidate its current usage and inform clinical, research, and policy recommendations. SUMMARY OF BACKGROUND DATA Degenerative disc disease has… read more here.
Keywords: degenerative disc; disease name; disc disease; term ... See more keywords
Circulating miR-155-5p as a Novel Biomarker of Lumbar Degenerative Disc Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Spine"
DOI: 10.1097/brs.0000000000003322
Abstract: MINI: Circulating microRNAs provide an insight into current disease states. Comparing patients with degenerative disc disease to healthy controls, patients with disc disease were found to have significantly downregulated levels of miR-155-5p. This marker was… read more here.
Keywords: mir 155; degenerative disc; disc disease; ddd ... See more keywords
Lumbar Puncture Increases Risk of Lumbar Degenerative Disc Disease: Analysis from the Rochester Epidemiology Project.
Sign Up to like & getrecommendations! Published in 2020 at "Spine"
DOI: 10.1097/brs.0000000000003595
Abstract: MINI: We performed a population-based retrospective cohort study that included 950 cases with lumbar puncture (LP) and 1876 matched control without LP, the proportion of degenerative disc disease (DDD) diagnosis was 20.5% with LP vs… read more here.
Keywords: lumbar puncture; degenerative disc; disc disease; risk ... See more keywords
Percutaneous Cement Discoplasty for the Treatment of Advanced Degenerative Disc Conditions: A Case Series Analysis
Sign Up to like & getrecommendations! Published in 2020 at "Global Spine Journal"
DOI: 10.1177/2192568219873885
Abstract: Study Design: Retrospective analysis. Level of evidence III. Objectives: To describe the results after a minimum 1-year follow-up in patients treated with percutaneous discoplasty (PD), a minimally invasive technique to treat low back pain in… read more here.
Keywords: discoplasty; advanced degenerative; analysis; degenerative disc ... See more keywords
Lumbar Fusion Surgery for Patients With Back Pain and Degenerative Disc Disease: An Observational Study From the Canadian Spine Outcomes and Research Network.
Sign Up to like & getrecommendations! Published in 2021 at "Global spine journal"
DOI: 10.1177/2192568220985470
Abstract: STUDY DESIGN Uncontrolled retrospective observational study. OBJECTIVES Surgery for patients with back pain and degenerative disc disease is controversial, and studies to date have yielded conflicting results. We evaluated the effects of lumbar fusion surgery… read more here.
Keywords: surgery; back pain; degenerative disc; disc disease ... See more keywords
Kinematic characteristics of lumbar spinous processes during axial rotation in patients with lumbar degenerative disc disease lateral lumbar interbody fusion and intervention
Sign Up to like & getrecommendations! Published in 2017 at "BMC Musculoskeletal Disorders"
DOI: 10.1186/s12891-017-1504-6
Abstract: BackgroundData about minimally invasive surgery for the treatment of patients with degenerative disc disease (DDD) has been reported. However, no quantitative knowledge about the biomechanical characteristics of the spinous processes in patients with DDD after… read more here.
Keywords: degenerative disc; rotation; disc disease; lumbar spinous ... See more keywords
Cortical bone trajectory screws in the treatment of lumbar degenerative disc disease in patients with osteoporosis
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i36.13179
Abstract: Lumbar degenerative disc disease (DDD) in the elderly population remains a global health problem, especially in patients with osteoporosis. Osteoporosis in the elderly can cause failure of internal fixation. Cortical bone trajectory (CBT) is an… read more here.
Keywords: lumbar; patients osteoporosis; degenerative disc; disc disease ... See more keywords
Loss of Pinch Proteins Causes Severe Degenerative Disc Disease-Like Lesions in Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Aging and disease"
DOI: 10.14336/ad.2023.0212
Abstract: Degenerative disc disease (DDD) is one of the most common skeletal disorders affecting aged populations. DDD is the leading cause of low back/neck pain, resulting in disability and huge socioeconomic burdens. However, the molecular mechanisms… read more here.
Keywords: like lesions; loss; degenerative disc; pinch proteins ... See more keywords
Is Propionibacterium acnes related to disc degeneration in adults? A systematic review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of neurosurgical sciences"
DOI: 10.23736/s0390-5616.16.03842-x
Abstract: BACKGROUND The aim of this paper was to systematically review the evidence linking Propionibacterium acnes (P. acnes) with the development of symptomatic degenerative disc disease. EVIDENCE ACQUISITION Data were obtained from MEDLINE from their inception… read more here.
Keywords: disc degeneration; degenerative disc; disc disease; symptomatic degenerative ... See more keywords
The Endplate Role in Degenerative Disc Disease Research: The Isolation of Human Chondrocytes from Vertebral Endplate—An Optimised Protocol
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9040137
Abstract: Background: Degenerative disc disease is a progressive and chronic disorder with many open questions regarding its pathomorphological mechanisms. In related studies, in vitro organ culture systems are becoming increasingly essential as a replacement option for… read more here.
Keywords: human chondrocytes; chondrocytes vertebral; degenerative disc; disc disease ... See more keywords