Pharmacotherapy for metabolic and cellular stress in degenerative retinal diseases.
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DOI: 10.1016/j.drudis.2019.11.013
Abstract: Retinal photoreceptors continually endure stresses associated with prolonged light exposure and the metabolic demands of dark adaptation. Although healthy photoreceptors are able to withstand these stresses for several decades, the disease-affected retina functions at a… read more here.
Keywords: degenerative retinal; metabolic cellular; cellular stress; pharmacotherapy metabolic ... See more keywords
Epigenetics and Degenerative Retinal Diseases: Prospects for New Therapeutic Approaches.
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DOI: 10.1097/apo.0000000000000520
Abstract: ABSTRACT There is growing evidence that retinal degenerative diseases are accompanied by epigenetic changes in both deoxyribonucleic acid methylation and histone modification. Even in the monogenic disease retinitis pigmentosa, there is a cascade of changes… read more here.
Keywords: new therapeutic; degenerative retinal; epigenetics degenerative; therapeutic approaches ... See more keywords
Recent developments of neuroprotective agents for degenerative retinal disorders
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DOI: 10.4103/1673-5374.335140
Abstract: Retinal degeneration is a debilitating ocular complication characterized by the progressive loss of photoreceptors and other retinal neurons, which are caused by a group of retinal diseases affecting various age groups, and increasingly prevalent in… read more here.
Keywords: degeneration; retinal disorders; degenerative retinal; retinal neurons ... See more keywords