Articles with "degradable immunotoxin" as a keyword



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Novel Oxygen-Dependent Degradable Immunotoxin Regulated by the Ubiquitin-Proteasome System Reduces Nonspecific Cytotoxicity.

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Published in 2022 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.2c00503

Abstract: The use of bacterial toxins as antitumor agents has received considerable attention. Immunotoxins based on antigen recognition of single-chain antibodies have been widely explored for cancer therapy. Despite their impressive killing effect on tumor cells,… read more here.

Keywords: oxygen dependent; ubiquitin proteasome; degradable immunotoxin; oxygen ... See more keywords