Articles with "degradation krasg12d" as a keyword



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Targeted Degradation of KRASG12D as Potential Therapy in Cancer.

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Published in 2023 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.3c00111

Abstract: Selective proteolysis represents a cutting-edge therapeutic approach that is garnering global interest due to its capacity to eradicate pathogenic biomolecules within cellular environments. For instance, the PROTAC technology brings the ubiquitin proteasome system degradation machinery… read more here.

Keywords: potential therapy; therapy cancer; krasg12d potential; targeted degradation ... See more keywords