Sildenafil triggers tumor lethality through altered expression of HSP90 and degradation of PKD2.
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DOI: 10.1093/carcin/bgaa001
Abstract: The repurposing of existing drugs has emerged as an attractive additional strategy to the development of novel compounds in the fight against cancerous diseases. Inhibition of Phosphodiesterase 5 has been claimed as a potential approach… read more here.
Keywords: cancer; degradation pkd2; altered expression; expression hsp90 ... See more keywords