Microbial degradation products of lurasidone and their significance in postmortem toxicology.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3441
Abstract: Recent research reported that lurasidone degrades in unpreserved ante-mortem human whole blood inoculated with microorganisms known to dominate postmortem blood specimens. In vitro degradation occurred at a similar rate to risperidone, known to degrade in… read more here.
Keywords: toxicology; postmortem; lurasidone degradation; degradation ... See more keywords
Degradation of Deoxynivalenol in Wheat by Double Dielectric Barrier Discharge Cold Plasma: Identification and Pathway of Degradation Products.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12393
Abstract: BACKGROUND Deoxynivalenol (DON) produced during the onset of fusarium head blight affects not only the quality and safety of wheat but also causes serious harm to human and livestock health. However, due to the high… read more here.
Keywords: wheat; cold plasma; c15; degradation ... See more keywords
Identification, isolation, and structural characterization of novel forced degradation products of apixaban using advanced analytical techniques.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of separation science"
DOI: 10.1002/jssc.202200466
Abstract: The current research explains the stress degradation behavior of Apixaban, which is an anticoagulant or blood thinner. The degradation was conducted using hydrolytic, oxidative, thermal, and photolytic conditions. Apixaban is relatively stable in oxidative, thermal,… read more here.
Keywords: spectroscopy; mass; degradation; degradation products ... See more keywords
Comparison of Different Lactobacilli Regarding Substrate Utilization and Their Tolerance Towards Lignocellulose Degradation Products
Sign Up to like & getrecommendations! Published in 2020 at "Current Microbiology"
DOI: 10.1007/s00284-020-02131-y
Abstract: Fermentative lactic acid production is currently impeded by low pH tolerance of the production organisms, the successive substrate consumption of the strains and/or the requirement to apply purified substrate streams. We identified Lactobacillus brevis IGB… read more here.
Keywords: acid; tolerance; brevis igb; degradation products ... See more keywords
Degradation Pathway Proposal, Structure Elucidation, and In Silico Toxicity Prediction of Dapagliflozin Propane Diol Hydrolytic Degradation Products
Sign Up to like & getrecommendations! Published in 2020 at "Chromatographia"
DOI: 10.1007/s10337-020-03938-4
Abstract: Dapagliflozin (DAP) is therapeutic agent for diabetes mellitus type II patients with insufficient glycemic control by exercise and diet. Stability-indicating LC–MS method was developed and validated on C8 column and method was able to separate… read more here.
Keywords: degradation; structure elucidation; hydrolytic degradation; silico toxicity ... See more keywords
Endocrine disruption: molecular interactions of chlorpyrifos and its degradation products with estrogen receptor
Sign Up to like & getrecommendations! Published in 2020 at "Structural Chemistry"
DOI: 10.1007/s11224-020-01562-4
Abstract: Chlorpyrifos is an extensively used organophosphate pesticide showing broad-spectrum effectiveness on various target pests. Long-term sublethal exposure to this pesticide is reported to produce detrimental effects on sex hormone metabolism and nervous system functioning. It… read more here.
Keywords: degradation; estrogen receptor; endocrine disruption; degradation products ... See more keywords
Preliminary Structural Analysis of High Molecular Weight Alkaline Degradation Products of Sucrose
Sign Up to like & getrecommendations! Published in 2021 at "Sugar Tech"
DOI: 10.1007/s12355-020-00902-2
Abstract: The high molecular weight alkaline degradation products of sucrose (HMWADPS) are the colored substances in sugar juice. Few studies have been conducted to elucidate the structure of HMWADPS. In the present study, the structure of HMWADPS… read more here.
Keywords: weight; degradation products; weight alkaline; high molecular ... See more keywords
SPE-LC-MS investigations for the isolation and fractionation of acidic oil degradation products.
Sign Up to like & getrecommendations! Published in 2018 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2018.06.074
Abstract: In this study, we focus on isolation and fractionation strategies by solid phase extraction (SPE) for a broad range of environmentally related organic acids. These emerging potential contaminants are primary degradation products of spilled petrogenic… read more here.
Keywords: fractionation; isolation fractionation; fractionation acidic; degradation products ... See more keywords
The degradation and transport mechanism of a Mg-Nd-Zn-Zr stent in rabbit common carotid artery: A 20-month study.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.01.018
Abstract: Mg-based stent is a promising candidate of the next generation fully degradable vascular stents. The latest progress includes the CE approval of the Magmaris ® WE43 based drug eluting stent. However, so far, the long… read more here.
Keywords: degradation; long term; common carotid; degradation products ... See more keywords
Effect of magnesium-degradation products and hypoxia on the angiogenesis of human umbilical vein endothelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.02.018
Abstract: Biodegradable magnesium (Mg) metals have been applied in orthopaedic and stent applications due to their biodegradability, bioabsorbability and adaptability to tissue regeneration. However, further investigations are still needed to understand how angiogenesis will respond to… read more here.
Keywords: degradation; angiogenesis; effect; magnesium ... See more keywords
Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sign Up to like & getrecommendations! Published in 2019 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2014.11.044
Abstract: Abstract In this stability-indicating, reversed-phase high-performance liquid chromatographic method for nicardipine (NIC), forced degradation has been employed and the formed degradants were separated on a C18 (150 mm × 3.9 mm, 5 μm) analytical column using a mobile phase consisted… read more here.
Keywords: degradation products; method; stability indicating; spiked human ... See more keywords