Kinetic Degradation Study of Dapagliflozin Coupled with UHPLC Separation in the Presence of Major Degradation Product and Metformin
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DOI: 10.1007/s10337-019-03702-3
Abstract: A novel ultra-performance liquid chromatography with UV detector technique was established for simultaneous determination of two antidiabetic drugs, dapagliflozin (DAPA) and metformin (MET), followed by a stress degradation study. Main degradation product was chromatographically separated… read more here.
Keywords: degradation; degradation product; metformin; degradation study ... See more keywords
Forced degradation study with a developed and validated RP-HPLC method for determination of cefpodoxime proxetil in the bulk and finished pharmaceutical products
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-019-01630-5
Abstract: The present study aimed to develop an HPLC method of Cfp analysis which enjoyed highly linearity, repeatability, robustness, ruggedness, selectivity, rapidly, and economic to use. The chromatographic method uses a column Inertsil ODS-3 (250 mm × 4.6 mm × 5 µm). The… read more here.
Keywords: forced degradation; bulk; method; degradation study ... See more keywords
Degradation study of a proton exchange membrane water electrolyzer under dynamic operation conditions
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DOI: 10.1016/j.apenergy.2020.115911
Abstract: Abstract Understanding degradation phenomena of polymer electrolyte water electrolyzers operating under dynamic conditions is imperative for developing and implementing efficient and reliable means of energy storage from fluctuating and intermittent renewable energy sources. Herein, a… read more here.
Keywords: water; dynamic operation; degradation study; membrane ... See more keywords
Stability Indicating Forced Degradation Studies
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DOI: 10.5958/0974-360x.2019.00078.7
Abstract: Forced degradation study (FD) studies (stress testing) are an intrinsic part of pharmaceutical product development. It is procedure whereby the natural degradation rate of a product or material is increased by the application of additional… read more here.
Keywords: development; stability indicating; degradation study; forced degradation ... See more keywords