ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD+-Mediated Epithelial-Mesenchymal Transition.
Sign Up to like & getrecommendations! Published in 2018 at "Cell chemical biology"
DOI: 10.1016/j.chembiol.2017.12.008
Abstract: Nicotinamide adenine dinucleotide (NAD) levels decrease with aging as a result of aging-associated CD38 upregulation. Here, we established a cell model with decreased cellular NAD levels by overexpressing CD38 or treating cells with FK866, an… read more here.
Keywords: degradation; mesenchymal transition; ros mediated; hydroxyprostaglandin dehydrogenase ... See more keywords
Cobalt nanoparticles encapsulated in nitrogen-rich carbon nanotubes as efficient catalysts for organic pollutants degradation via sulfite activation.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2018.03.040
Abstract: The activation of sulfite by heterogeneous catalysts displays a great potential in the development of new sulfate radials based technologies for wastewater treatment. Herein, cobalt nanoparticles embedded in N-doped carbon nanotubes (Co@NC) were prepared by… read more here.
Keywords: carbon; carbon nanotubes; cobalt nanoparticles; degradation via ... See more keywords
The role of reactive oxygen species and carbonate radical in oxcarbazepine degradation via UV, UV/H2O2: Kinetics, mechanisms and toxicity evaluation.
Sign Up to like & getrecommendations! Published in 2018 at "Water research"
DOI: 10.1016/j.watres.2018.10.007
Abstract: Oxcarbazepine (OXC) is ubiquitous in the aqueous environment. And due to its ecotoxicological effects and potential risks to human, an effective way to eliminate OXC from aqueous environment has aroused public concerns in recent years.… read more here.
Keywords: oxygen; degradation; oxc degradation; degradation via ... See more keywords
Targeted Protein Degradation via Lysosomes.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00310
Abstract: In the scope of targeted protein degradation (TPD), proteolysis-targeting chimeras (PROTACs), leveraging the ubiquitin-proteasome system, have been extensively studied. However, they are limited to the degradation of soluble and membrane proteins, excluding the aggregated and… read more here.
Keywords: degradation via; targeted protein; protein degradation; degradation ... See more keywords
Extracellular protein degradation via the lysosome
Sign Up to like & getrecommendations! Published in 2020 at "Communications Chemistry"
DOI: 10.1038/s42004-020-00397-8
Abstract: Tight regulation of protein levels is so crucial for cellular function that mammalian cells have evolved two parallel degradation systems. This article discusses how these systems can be exploited to selectively target proteins of interest… read more here.
Keywords: protein; degradation; via lysosome; extracellular protein ... See more keywords