A Versatile and Sustainable Multicomponent Platform for the Synthesis of Protein Degraders: Proof-of-Concept Application to BRD4-Degrading PROTACs
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DOI: 10.1021/acs.jmedchem.2c01218
Abstract: The use of small molecules to induce targeted protein degradation is increasingly growing in the drug discovery landscape, and protein degraders have progressed rapidly through the pipelines. Despite the advances made so far, their synthesis… read more here.
Keywords: protacs; synthesis; protein degraders; degrading protacs ... See more keywords