Determination of modification degree of polysialylated therapeutic proteins using 1H-NMR spectroscopy.
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DOI: 10.1016/j.ijbiomac.2021.06.165
Abstract: Water soluble polymers and their derivatives bound to proteins can dramatically favor the biological activity of new drugs and vaccines. Quantification of the modification degree of the protein is crucial during the development and licensing… read more here.
Keywords: degree polysialylated; modification degree; proteins using; spectroscopy ... See more keywords