Clustering of Neuropsychiatric Disease in First-Degree and Second-Degree Relatives of Patients With Amyotrophic Lateral Sclerosis
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.2699
Abstract: Importance Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative condition primarily involving the motor system. There is increasing epidemiologic evidence of an association between ALS and a wider spectrum of neurodegenerative and neuropsychiatric disorders among… read more here.
Keywords: degree relatives; first degree; second degree; relatives patients ... See more keywords
Risk of Syndrome-Associated Cancers Among First-Degree Relatives of Patients With Pancreatic Ductal Adenocarcinoma With Pathogenic or Likely Pathogenic Germline Variants.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2023.0806
Abstract: Importance Increased cancer risk in first-degree relatives of probands with pancreatic ductal adenocarcinoma (PDAC probands) who carry pathogenic or likely pathogenic germline variants (PGVs) in cancer syndrome-associated genes encourages cascade genetic testing. To date, unbiased… read more here.
Keywords: pdac probands; syndrome associated; degree relatives; first degree ... See more keywords
High prevalence of diabetes‐specific autoimmunity in first‐degree relatives of Sardinian patients with type 1 diabetes
Sign Up to like & getrecommendations! Published in 2017 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.2864
Abstract: The incidence of type 1 diabetes mellitus (T1DM) in Sardinia is among the highest in the world (44.8 cases/100,000 person‐years). Recommendations of the Immunology of Diabetes Society advise evaluating autoantibody positivity in first‐degree relatives (FDRs)… read more here.
Keywords: degree relatives; first degree; high prevalence; type diabetes ... See more keywords
Familial implications of autoimmune disease: Recurrence risks of alopecia areata and associated conditions in first‐degree relatives
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Genetic Counseling"
DOI: 10.1002/jgc4.1178
Abstract: Alopecia areata (AA), a complex autoimmune hair loss condition, affects approximately 2.1% of the population. Individuals with AA have increased susceptibility to diseases such as atopy and autoimmune disorders, but little is known about first‐degree… read more here.
Keywords: degree relatives; alopecia areata; associated conditions; first degree ... See more keywords
Fatalism and metaphor in Confucianism: A qualitative study of barriers to genetic testing among first‐degree relatives of hereditary cancer patients from China
Sign Up to like & getrecommendations! Published in 2022 at "Psycho-Oncology"
DOI: 10.1002/pon.6068
Abstract: Despite the benefits, the rate of genetic testing among first‐degree relatives (FDRs; parents, children, and siblings) remains low, and the barriers to undergoing testing among FDRs in China are not clear. We explored the reasons… read more here.
Keywords: degree relatives; genetic testing; first degree; testing among ... See more keywords
High frequency of rheumatic regional pain syndromes in first-degree relatives of patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05029-z
Abstract: First-degree relatives (FDR) of patients with rheumatoid arthritis (RA) have a higher risk for the development of RA. In the stages prior to the development of arthritis, nonspecific musculoskeletal (MSK) manifestations may occur. The aim… read more here.
Keywords: degree relatives; first degree; pain; rheumatoid arthritis ... See more keywords
Outcomes of screening gastroscopy in first-degree relatives of patients fulfilling hereditary diffuse gastric cancer criteria.
Sign Up to like & getrecommendations! Published in 2018 at "Gastrointestinal endoscopy"
DOI: 10.1016/j.gie.2017.04.016
Abstract: BACKGROUND AND AIMS The aim of this study was to determine the yield of endoscopic screening in first-degree relatives (FDRs) of CDH1-negative hereditary diffuse-type gastric cancer (HDGC) patients. METHODS In this retrospective observational cohort study,… read more here.
Keywords: diffuse; degree relatives; first degree; gastric cancer ... See more keywords
Aberrant probabilistic reinforcement learning in first-degree relatives of individuals with bipolar disorder.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of affective disorders"
DOI: 10.1016/j.jad.2019.11.063
Abstract: BACKGROUND Motivational dysregulation represents a core vulnerability factor for bipolar disorder. Whether this also comprises aberrant learning of stimulus-reinforcer contingencies is less clear. METHODS To answer this question, we compared healthy first-degree relatives of individuals… read more here.
Keywords: degree relatives; first degree; disorder; reinforcement learning ... See more keywords
Higher-order language dysfunctions as a possible neurolinguistic endophenotype for schizophrenia: Evidence from patients and their unaffected first degree relatives.
Sign Up to like & getrecommendations! Published in 2018 at "Psychiatry Research"
DOI: 10.1016/j.psychres.2018.05.070
Abstract: The purpose of the study was to examine the presence of pragmatic dysfunctions in first episode (FE) subjects and their healthy first degree relatives as a potential endophenotype for schizophrenia. Thirty-four FE patients, 34 parents… read more here.
Keywords: degree relatives; schizophrenia; first degree; endophenotype schizophrenia ... See more keywords
Altered parahippocampal gyrus activation and its connectivity with resting-state network areas in schizophrenia: An EEG study
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2020.03.066
Abstract: Synchronized and coherent activity in resting-networks during normal brain functioning could be altered in disconnection syndrome like schizophrenia. Study of neural oscillations as assessed by EEG appears to be a promising proposition to understand the… read more here.
Keywords: state; degree relatives; first degree; study ... See more keywords
Longitudinal study of narcolepsy symptoms in first, second, and third-degree relatives of simplex and multiplex narcolepsy families.
Sign Up to like & getrecommendations! Published in 2019 at "Sleep medicine"
DOI: 10.1016/j.sleep.2018.06.015
Abstract: OBJECTIVE To assess the evolution of narcolepsy symptoms in first-, second, and third-degree relatives and to compare multiplex and simplex families. METHODS A total of 4045 family members and 362 narcoleptic individuals were entered in… read more here.
Keywords: degree relatives; multiplex families; first second; narcolepsy symptoms ... See more keywords