Identification of key genes in benign prostatic hyperplasia using bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2021 at "World Journal of Urology"
DOI: 10.1007/s00345-021-03625-5
Abstract: This study aimed to identify differentially expressed genes (DEGs) and pathways in benign prostatic hyperplasia (BPH) by comprehensive bioinformatics analysis. Data of the gene expression microarray (GSE6099) were downloaded from GEO database. DEGs were obtained… read more here.
Keywords: degs; benign prostatic; analysis; bioinformatics analysis ... See more keywords
Bioinformatics analyses of gene expression profile identify key genes and functional pathways involved in cutaneous lupus erythematosus
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05913-2
Abstract: Lupus erythematosus is an autoimmune disease that causes damage to multiple organs ranging from skin lesions to systemic manifestations. Cutaneous lupus erythematosus (CLE) is a common type of lupus erythematosus (LE), but its molecular mechanisms… read more here.
Keywords: degs; analysis; lupus erythematosus; cle ... See more keywords
Transcriptome analysis of potato shoots, roots and stolons under nitrogen stress
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-58167-4
Abstract: Potato crop requires high dose of nitrogen (N) to produce high tuber yield. Excessive application of N causes environmental pollution and increases cost of production. Hence, knowledge about genes and regulatory elements is essential to… read more here.
Keywords: protein; roots stolons; degs; analysis ... See more keywords
Identifications of potential therapeutic targets and drugs in angiotensin II-induced hypertension
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DOI: 10.1097/md.0000000000008501
Abstract: Abstract This study aimed to identify the underlying therapeutic targets of angiotensin II (AngII)-induced hypertension, and screen the related drugs. The gene expression profiles of GSE93579 and GSE75815 were used to identify differentially expressed genes… read more here.
Keywords: induced hypertension; degs; mir; therapeutic targets ... See more keywords
Analysis of Potential Genes and Pathways Involved in the Pathogenesis of Acne by Bioinformatics
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DOI: 10.1155/2019/3739086
Abstract: Acne is the eighth most frequent disease worldwide. Inflammatory response runs through all stages of acne. It is complicated and is involved in innate and adaptive immunity. This study aimed to explore the candidate genes… read more here.
Keywords: degs; analysis; pathogenesis; pathways involved ... See more keywords
Sex Difference of Ribosome in Stroke-Induced Peripheral Immunosuppression by Integrated Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/3650935
Abstract: Ischemic stroke (IS) greatly threatens human health resulting in high mortality and substantial loss of function. Recent studies have shown that the outcome of IS has sex specific, but its mechanism is still unclear. This… read more here.
Keywords: degs; analysis; stroke induced; sex ... See more keywords
Identification of Key Genes in Nasopharyngeal Carcinoma Based on Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Computational Intelligence and Neuroscience"
DOI: 10.1155/2022/9022700
Abstract: Objective This study aimed to identify key genes associated with the pathogenesis of nasopharyngeal carcinoma (NPC) by bioinformatics analysis. Methods Datasets (GSE13597 and GSE34573) were screened and downloaded from the comprehensive gene expression database (GEO).… read more here.
Keywords: nasopharyngeal carcinoma; bioinformatics analysis; key genes; degs ... See more keywords
A comparison of shared patterns of differential gene expression and gene ontologies in response to water-stress in roots and leaves of four diverse genotypes of Lolium and Festuca spp. temperate pasture grasses
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0249636
Abstract: Ryegrasses (Lolium spp.) and fescues (Festuca spp.) are closely related and widely cultivated perennial forage grasses. As such, resilience in the face of abiotic stresses is an important component of their traits. We have compared… read more here.
Keywords: water stress; festuca spp; degs; water ... See more keywords
Mitochondria dysfunction in airway epithelial cells is associated with type 2-low asthma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1186317
Abstract: Background: Type 2 (T2)-low asthma can be severe and corticosteroid-resistant. Airway epithelial cells play a pivotal role in the development of asthma, and mitochondria dysfunction is involved in the pathogenesis of asthma. However, the role… read more here.
Keywords: airway epithelial; asthma; low asthma; degs ... See more keywords
Blood transcriptome analysis revealed the crosstalk between COVID-19 and HIV
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1008653
Abstract: Background The severe coronavirus disease 2019 (COVID-19) is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has resulted in the most devastating pandemic in modern history. Human immunodeficiency virus… read more here.
Keywords: hiv; covid; covid hiv; analysis ... See more keywords
DegS protease regulates the motility, chemotaxis, and colonization of Vibrio cholerae
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1159986
Abstract: In bacteria, DegS protease functions as an activating factor of the σE envelope stress response system, which ultimately activates the transcription of stress response genes in the cytoplasm. On the basis of high-throughput RNA sequencing,… read more here.
Keywords: motility chemotaxis; colonization; cholerae; degs ... See more keywords