Di‐(2‐ethylhexyl) phthalate (DEHP)‐induced testicular toxicity through Nrf2‐mediated Notch1 signaling pathway in Sprague–Dawley rats
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Toxicology"
DOI: 10.1002/tox.22559
Abstract: Di‐(2‐ethylhexyl) phthalate (DEHP) is an environmental endocrine disruptor widely used in China that is harmful to the male reproductive system. Many studies have shown that DEHP causes testicular toxicity through oxidative stress, but the specific… read more here.
Keywords: dehp induced; testicular toxicity; toxicity; pathway ... See more keywords
Lycopene prevents DEHP-induced Leydig cell damage with the Nrf2 antioxidant signaling pathway in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b06882
Abstract: As a plasticizer, di(2-ethylhexyl) phthalate (DEHP) is the most usually used phthalates. Leydig cell is a male-specific cell, which plays a principal role in spermatogenesis and masculinization by androgens of synthesis and secretion. Numerous researchers… read more here.
Keywords: leydig cell; dehp induced; cell; cell damage ... See more keywords
The Protective Effect of Trichilia catigua A. Juss. on DEHP-Induced Reproductive System Damage in Male Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.832789
Abstract: The present study aimed to explore the protective effect and molecular mechanisms of Trichilia catigua A. Juss. extract (TCE) against di (2-ethylhexyl) phthalate (DEHP)-induced damage to the reproductive system of mice. Acute toxicity tests revealed… read more here.
Keywords: tce; tce tce; reproductive system; dehp induced ... See more keywords