The N‐terminal domains of the paralogous HycE and NuoCD govern assembly of the respective formate hydrogenlyase and NADH dehydrogenase complexes
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DOI: 10.1002/2211-5463.12787
Abstract: Formate hydrogenlyase (FHL) is the main hydrogen‐producing enzyme complex in enterobacteria. It converts formate to CO2 and H2 via a formate dehydrogenase and a [NiFe]‐hydrogenase. FHL and complex I are evolutionarily related and share a… read more here.
Keywords: terminal domains; dehydrogenase; formate hydrogenlyase; domains paralogous ... See more keywords
The effect of brimonidine and proparacaine on metabolic enzymes: Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2107
Abstract: Oxidative stress is to upregulate the pentose phosphate pathway (PPP). The PPP consists of two functionally branches, glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase (6PGD). Glutathione reductase (GR) has a significant role in catalyzing an oxidized… read more here.
Keywords: dehydrogenase; phosphate dehydrogenase; glucose phosphate; brimonidine proparacaine ... See more keywords
Improved performance of Pseudomonas putida in a bioelectrochemical system through overexpression of periplasmic glucose dehydrogenase
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DOI: 10.1002/bit.26433
Abstract: It was recently demonstrated that a bioelectrochemical system (BES) with a redox mediator allowed Pseudomonas putida to perform anoxic metabolism, converting sugar to sugar acids with high yield. However, the low productivity currently limits the… read more here.
Keywords: dehydrogenase; system; glucose dehydrogenase; productivity ... See more keywords
Enhancing cofactor recycling in the bioconversion of racemic alcohols to chiral amines with alcohol dehydrogenase and amine dehydrogenase by coupling cells and cell‐free system
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DOI: 10.1002/bit.26896
Abstract: Alcohol dehydrogenase (ADH) and amine dehydrogenase (AmDH)‐catalyzed one‐pot cascade conversion of an alcohol to an amine provides a simple preparation of chiral amines. To enhance the cofactor recycling in this reaction, we report a new… read more here.
Keywords: dehydrogenase; racemic alcohols; conversion; alcohol dehydrogenase ... See more keywords
Production of retinoic acid by engineered Saccharomyces cerevisiae using an endogenous aldehyde dehydrogenase
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28192
Abstract: Retinoic acid (RA), a vitamin A (retinol)‐derived lipophilic compound, is involved in various physiological functions. The demand for RA is growing in the pharmaceutical industry, but RA biosynthesis is still in its infancy compared to… read more here.
Keywords: aldehyde dehydrogenase; dehydrogenase; retinoic acid; endogenous aldehyde ... See more keywords
Fusion of Formate Dehydrogenase and Alanine Dehydrogenase as an Amino Donor Regenerating System Coupled to Transaminases
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DOI: 10.1002/cbic.202200428
Abstract: Fusion enzymes are attractive tools for facilitating the assembly of biocatalytic cascades for chemical synthesis. This approach can offer great advantages for cooperative redox cascades that need the constant supply of a donor molecule. In… read more here.
Keywords: dehydrogenase; system; fusion; amino donor ... See more keywords
Coupled Immobilized Amine Dehydrogenase and Glucose Dehydrogenase for Asymmetric Synthesis of Amines by Reductive Amination with Cofactor Recycling
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DOI: 10.1002/cctc.201601446
Abstract: The amine dehydrogenase (AmDH) engineered from the phenylalanine dehydrogenase of Rhodococcus sp. M4 was directly immobilized on magnetic nanoparticles (MNP) from the cell‐free extract containing his‐tagged AmDH through affinity attachment to give AmDH‐MNPs with high… read more here.
Keywords: dehydrogenase; glucose dehydrogenase; amdh; reductive amination ... See more keywords
Microenvironmental control of glucose metabolism in tumors by regulation of pyruvate dehydrogenase
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DOI: 10.1002/ijc.31812
Abstract: During malignant progression cancer cells undergo a series of changes, which promote their survival, invasiveness and metastatic process. One of them is a change in glucose metabolism. Unlike normal cells, which mostly rely on the… read more here.
Keywords: microenvironmental control; dehydrogenase; glucose metabolism; cancer ... See more keywords
CHIP control degradation of mutant ETF:QO through ubiquitylation in late‐onset multiple acyl‐CoA dehydrogenase deficiency
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DOI: 10.1002/jimd.12361
Abstract: Late‐onset multiple acyl‐CoA dehydrogenase deficiency (MADD) is the most common form of lipid storage myopathy. The disease is mainly caused by mutations in electron‐transfer flavoprotein dehydrogenase gene (ETFDH), which leads to decreased levels of ETF:QO… read more here.
Keywords: mutant etf; late onset; dehydrogenase; degradation mutant ... See more keywords
Application of denaturing capillary electrophoresis for the detection of prognostic mutations in isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 genes in brain tumors.
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DOI: 10.1002/jssc.201701473
Abstract: Malignant transformation in gliomas is frequently supplemented by somatic mutations in isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 genes. It has recently emerged that mutations in these genes are associated with prolonged survival and should… read more here.
Keywords: capillary electrophoresis; dehydrogenase; detection; isocitrate dehydrogenase ... See more keywords
Correlation between lactate dehydrogenase/pyruvate dehydrogenase activities ratio and tissue pH in the perfused mouse heart: A potential noninvasive indicator of cardiac pH provided by hyperpolarized magnetic resonance
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DOI: 10.1002/nbm.4444
Abstract: Cardiovascular diseases account for more than 30% of all deaths worldwide and many could be ameliorated with early diagnosis. Current cardiac imaging modalities can assess blood flow, heart anatomy and mechanical function. However, for early… read more here.
Keywords: dehydrogenase; heart; tissue; correlation ... See more keywords