Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1
Sign Up to like & getrecommendations! Published in 2017 at "Haematologica"
DOI: 10.3324/haematol.2016.159053
Abstract: Aldehyde dehydrogenase 1A1 (ALDH1A1) activity is high in hematopoietic stem cells and functions in part to protect stem cells from reactive aldehydes and other toxic compounds. In contrast, we found that approximately 25% of all… read more here.
Keywords: subset acute; acute myeloid; dehydrogenase 1a1; aldehyde dehydrogenase ... See more keywords
Aldehyde dehydrogenase 1A1 confers erlotinib resistance via facilitating the reactive oxygen species-reactive carbonyl species metabolic pathway in lung adenocarcinomas: Erratum
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DOI: 10.7150/thno.84874
Abstract: [This corrects the article DOI: 10.7150/thno.35729.]. read more here.
Keywords: resistance via; aldehyde dehydrogenase; erlotinib resistance; confers erlotinib ... See more keywords