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Published in 2022 at "Gene"
DOI: 10.1016/j.gene.2022.146497
Abstract: PURPOSE Mitochondrial isocitrate dehydrogenase (IDH2) is a major contributor to cellular redox control. The aim of this study was to preliminary link IDH2 genetic variations to redox imbalance, atherogenesis and risk of acute myocardial infarction…
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Keywords:
genetic variations;
dehydrogenase idh2;
mitochondrial isocitrate;
idh2 ... See more keywords
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Published in 2021 at "British Journal of Haematology"
DOI: 10.1111/bjh.17981
Abstract: Although we earlier reported a very poor outcome for younger adult patients with isocitrate dehydrogenase 2 (IDH2)R172‐mutated acute myeloid leukaemia (AML) entered into UK trials compared to IDH2WT and IDH2R140‐mutated patients, this was not corroborated…
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Keywords:
acute myeloid;
dehydrogenase idh2;
isocitrate dehydrogenase;
myeloid leukaemia ... See more keywords