Glucose 6-phosphate dehydrogenase inhibition sensitizes melanoma cells to metformin treatment
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DOI: 10.1016/j.tranon.2020.100842
Abstract: Most cancer cells exacerbate the pentose phosphate pathway (PPP) to enhance biosynthetic precursors and antioxidant defenses. Metformin, which is used as a first-line oral drug for the treatment of type 2 diabetes, has been proposed… read more here.
Keywords: inhibition sensitizes; phosphate dehydrogenase; treatment; inhibition ... See more keywords