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   Articles with "del 20q" as a keyword



Prognostic impact of somatic mutations and additional chromosomal abnormalities in patients with myelodysplastic syndromes and chromosome 20q deletion

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recommendations! Published in 2025 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-025-01742-8

Abstract: The 20q deletion (del(20q)) is a recurrent chromosomal abnormality in individuals with myelodysplastic syndrome (MDS) and is associated with favourable outcomes when isolated. This study aims to analyse the clinical features and prognostic impact of… read more here.

Keywords: prognostic impact; del; 20q deletion; del 20q ... See more keywords

Expression analysis of genes located within the common deleted region of del(20q) in patients with myelodysplastic syndromes.

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recommendations! Published in 2019 at "Leukemia research"

DOI: 10.1016/j.leukres.2019.106175

Abstract: Deletion of the long arm of chromosome 20 (del(20q)) is observed in 5-10% of patients with myelodysplastic syndromes (MDS). We examined the expression of 28 genes within the common deleted region (CDR) of del(20q), which… read more here.

Keywords: myelodysplastic syndromes; patients myelodysplastic; within common; common deleted ... See more keywords
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The significance of genetic mutations and their prognostic impact on patients with incidental finding of isolated del(20q) in bone marrow without morphologic evidence of a myeloid neoplasm

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recommendations! Published in 2020 at "Blood Cancer Journal"

DOI: 10.1038/s41408-020-0275-8

Abstract: Patients with a sole del(20q) chromosomal abnormality and without morphologic features of a myeloid neoplasm (MN) have shown variable clinical outcomes. To explore the potential risk stratification markers in this group of patients, we evaluated… read more here.

Keywords: isolated del; without morphologic; myeloid neoplasm; del 20q ... See more keywords
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Inflammation in del(20q): a MST opportunity?

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood.2019003028

Abstract: In this issue of Blood, Stoner et al identify aberrant activation of inflammatory signaling pathways as a result of the Hippo kinase, MST1, loss in myeloid malignancies with deletion of chromosome 20q.(1) read more here.

Keywords: del 20q; 20q mst; inflammation del; mst opportunity ... See more keywords