Expression analysis of genes located within the common deleted region of del(20q) in patients with myelodysplastic syndromes.
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DOI: 10.1016/j.leukres.2019.106175
Abstract: Deletion of the long arm of chromosome 20 (del(20q)) is observed in 5-10% of patients with myelodysplastic syndromes (MDS). We examined the expression of 28 genes within the common deleted region (CDR) of del(20q), which… read more here.
Keywords: myelodysplastic syndromes; patients myelodysplastic; within common; common deleted ... See more keywords
The significance of genetic mutations and their prognostic impact on patients with incidental finding of isolated del(20q) in bone marrow without morphologic evidence of a myeloid neoplasm
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DOI: 10.1038/s41408-020-0275-8
Abstract: Patients with a sole del(20q) chromosomal abnormality and without morphologic features of a myeloid neoplasm (MN) have shown variable clinical outcomes. To explore the potential risk stratification markers in this group of patients, we evaluated… read more here.
Keywords: isolated del; without morphologic; myeloid neoplasm; del 20q ... See more keywords
Inflammation in del(20q): a MST opportunity?
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DOI: 10.1182/blood.2019003028
Abstract: In this issue of Blood, Stoner et al identify aberrant activation of inflammatory signaling pathways as a result of the Hippo kinase, MST1, loss in myeloid malignancies with deletion of chromosome 20q.(1) read more here.
Keywords: del 20q; 20q mst; inflammation del; mst opportunity ... See more keywords