Germline Chd8 haploinsufficiency alters brain development in mouse
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DOI: 10.1038/nn.4592
Abstract: The chromatin remodeling gene CHD8 represents a central node in neurodevelopmental gene networks implicated in autism. We examined the impact of germline heterozygous frameshift Chd8 mutation on neurodevelopment in mice. Chd8+/del5 mice displayed normal social… read more here.
Keywords: del5 mice; chd8; chd8 del5; brain development ... See more keywords