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Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12630
Abstract: Tumors and neutrophils undergo an unexpected interaction, in which products released by tumor cells interact to support neutrophils that in turn support cancer growth, angiogenesis, and metastasis. A key protein that is highly expressed by…
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Keywords:
cancer;
cancer associated;
delayed apoptosis;
protumorigenic neutrophils ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.836754
Abstract: Neutrophils (polymorphonuclear leukocytes, PMNs) have a distinctively short lifespan, and tight regulation of cell survival and death is imperative for their normal function. We demonstrated previously that Francisella tularensis extends human neutrophil lifespan, which elicits…
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Keywords:
apoptosis;
delayed apoptosis;
metabolic reprogramming;
tularensis ... See more keywords