Delayed death in the malaria parasite Plasmodium falciparum is caused by disruption of prenylation-dependent intracellular trafficking
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DOI: 10.1371/journal.pbio.3000376
Abstract: Apicomplexan parasites possess a plastid organelle called the apicoplast. Inhibitors that selectively target apicoplast housekeeping functions, including DNA replication and protein translation, are lethal for the parasite, and several (doxycycline, clindamycin, and azithromycin) are in… read more here.
Keywords: malaria parasite; death; digestive vacuole; disruption ... See more keywords