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Delayed Dosing of S-033188, a Novel Inhibitor of Influenza Virus Cap-dependent Endonuclease, Exhibited Significant Reduction of Viral Titer and Mortality in Mice Infected with Influenza A Virus

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Published in 2017 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofx163.1210

Abstract: Abstract Background Both epidemic and pandemic influenza are major public health concerns, but current standard treatment limits its usage by 48 hours from onsets. Furthermore, no antiviral drug has been shown to definitively reduce serious… read more here.

Keywords: dosing 033188; mortality; oseltamivir phosphate; influenza virus ... See more keywords