JNK inhibition alleviates delayed neurocognitive recovery after surgery by limiting microglia pyroptosis.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107962
Abstract: Delayed neurocognitive recovery (dNCR) is a prevalent complication after surgery in older adults. Neuroinflammation plays a pivotal role in the pathogenesis of dNCR. Recently,compelling evidence suggests that theinvolvement of microglia pyroptosis in the regulation of… read more here.
Keywords: surgery; pyroptosis; delayed neurocognitive; neurocognitive recovery ... See more keywords
ABCA7 rs3764650 Polymorphism is Associated with Delayed Neurocognitive Recovery
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s352810
Abstract: Background Several studies have shown that ATP-binding cassette transporter A7 (ABCA7) gene variation is associated with cognitive impairment. This study was aimed to investigate the relationship between ABCA7 rs3764650 polymorphism and perioperative neurocognitive disorder (pNCD).… read more here.
Keywords: neurocognitive recovery; delayed neurocognitive; rs3764650 polymorphism; polymorphism ... See more keywords
The Non-peptide Angiotensin-(1–7) Mimic AVE 0991 Attenuates Delayed Neurocognitive Recovery After Laparotomy by Reducing Neuroinflammation and Restoring Blood-Brain Barrier Integrity in Aged Rats
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2021.624387
Abstract: Delayed neurocognitive recovery (dNCR) after surgery is a common postoperative complication in older adult patients. Our previous studies have demonstrated that cognitive impairment after surgery involves an increase in the brain renin-angiotensin system (RAS) activity,… read more here.
Keywords: surgery; neuroinflammation; delayed neurocognitive; integrity ... See more keywords