Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed-Release Formulation of Esomeprazole in Healthy Subjects.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1237
Abstract: A novel dual delayed-release formulation (DR) of esomeprazole was developed to prolong the effect of esomeprazole inhibiting gastric acid secretion. This study investigated the effect of food on the pharmacokinetics (PK) and pharmacodynamics (PD) of… read more here.
Keywords: dual delayed; effect; delayed release; food ... See more keywords
A Retrospective Analysis of Real-World Discontinuation Rates with Delayed-Release Dimethyl Fumarate in Patients with Relapsing–Remitting Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Neurology and Therapy"
DOI: 10.1007/s40120-019-00174-3
Abstract: Introduction The main objective of this study was to examine discontinuation rates associated with delayed-release dimethyl fumarate (DMF) when used for the treatment of relapsing multiple sclerosis (MS) in a real-world, clinical practice setting. Methods… read more here.
Keywords: real world; dmf; discontinuation; discontinuation rates ... See more keywords
Embedment of liposomes into chitosan physical hydrogel for the delayed release of antibiotics or anaesthetics, and its first ESEM characterization.
Sign Up to like & getrecommendations! Published in 2020 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2019.115532
Abstract: This work describes the characterization of an original liposomes/hydrogel assembly, and its application as a delayed-release system of antibiotics and anaesthetics. This system corresponds to drug-loaded liposomes entrapped within a chitosan (CS) physical hydrogel. To… read more here.
Keywords: hydrogel; physical hydrogel; antibiotics anaesthetics; chitosan physical ... See more keywords
Achieving delayed release of freeze-dried probiotic strains by extrusion, spheronization and fluid bed coating - evaluated using a three-step in vitro model.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.120022
Abstract: Intake of probiotics is associated with many health benefits, which has generated an interest in formulating viable probiotic supplements. The present study had two aims. The first aim was to achieve gastrointestinal protection and delayed… read more here.
Keywords: three step; step; model; freeze dried ... See more keywords
Development and characterization of methylprednisolone loaded delayed release nanofibers
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2018.10.031
Abstract: Abstract Nanofibers have gained significant attention recently due to its wide applications in pharmaceutical area. Methylprednisolone (MP), a synthetic corticosteroid drug, has been used to treat a number of diseases. However, MP can lead to… read more here.
Keywords: release nanofibers; drug; release drug; delayed release ... See more keywords
Prevention of Invasive Aspergillus Fungal Infections with the Suspension and Delayed-Release Tablet Formulations of Posaconazole in Patients with Haematologic Malignancies
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DOI: 10.1038/s41598-018-20136-3
Abstract: Posaconazole is a triazole antifungal used to prevent invasive fungal infections (IFIs) in patients receiving chemotherapy or haemotopoietic stem cell transplantation. Due to highly variable bioavailability of the oral suspension formulation, a delayed-release tablet was… read more here.
Keywords: fungal infections; suspension; patients haematologic; delayed release ... See more keywords
Coating of sodium percarbonate particles using water soluble materials in a fluidised bed to achieve delayed release in aqueous environment
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DOI: 10.1080/23311916.2017.1372730
Abstract: Abstract Three coating materials, namely sodium sulphate, 1.6R and 2.35R sodium silicate, were respectively used to coat sodium percarbonate (SPC) particles in a fluidised bed coater to achieve its delayed release in aqueous environment. The… read more here.
Keywords: sodium; sodium silicate; delayed release; spc ... See more keywords
Therapeutic drug monitoring and adverse events of delayed-release posaconazole tablets in patients with chronic pulmonary aspergillosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dky539
Abstract: BACKGROUND Posaconazole delayed-release tablets offer better bioavailability than the liquid suspension, but no post-marketing data are available in immunocompetent hosts such as those with chronic pulmonary aspergillosis (CPA). OBJECTIVES To explore the pharmacokinetics and adverse… read more here.
Keywords: posaconazole tablets; chronic pulmonary; aspergillosis; pulmonary aspergillosis ... See more keywords
Pharmacokinetic and pharmacodynamic exploration of various combinations of tegoprazan immediate and delayed release formulations.
Sign Up to like & getrecommendations! Published in 2023 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.15784
Abstract: AIM The new modified-release formulation of tegoprazan, a novel potassium-competitive acid blocker, is expected to improve the management of acid-related disease, including nocturnal acid breakthrough, by prolonging the duration of acid suppression. This study aimed… read more here.
Keywords: release formulations; delayed release; acid; release ... See more keywords
Efficacy of Crushed Delayed-Release Posaconazole Tablets in Rhino-Orbito-Cerebral Mucormycosis
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DOI: 10.1128/aac.01085-22
Abstract: A significant proportion of patients with Rhino-orbito-cerebral mucormycosis (ROCM) develop oroantral fistulas. Due to the unclear efficacy of crushed delayed-release posaconazole tablets (DRPT) via nasogastric tube in this group of patients, clinicians often use inferior… read more here.
Keywords: orbito cerebral; delayed release; rhino orbito; crushed delayed ... See more keywords
Effect of Isavuconazonium Sulfate and Posaconazole Delayed Release Tablets on Tacrolimus Dose-to-Concentration Ratios
Sign Up to like & getrecommendations! Published in 2022 at "Progress in Transplantation"
DOI: 10.1177/15269248221145036
Abstract: Introduction Limited evidence exists on the effect of isavuconazonium sulfate and posaconazole delayed release tablets on tacrolimus dose-to-concentration ratios in lung transplant recipients. Project Aims The purpose of this evaluation was to assess the impact… read more here.
Keywords: delayed release; dose concentration; posaconazole delayed; release tablets ... See more keywords