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The Quinazoline Otaplimastat (SP-8203) Reduces the Hemorrhagic Transformation and Mortality Aggravated after Delayed rtPA-Induced Thrombolysis in Cerebral Ischemia

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23031403

Abstract: Acute ischemic stroke is the leading cause of morbidity and mortality worldwide. Recombinant tissue plasminogen activator (rtPA) is the only agent clinically approved by FDA for patients with acute ischemic stroke. However, delayed treatment of… read more here.

Keywords: delayed rtpa; ischemia; rtpa; hemorrhagic transformation ... See more keywords