Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells
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DOI: 10.1371/journal.pone.0204784
Abstract: Background aims Delaying replicative senescence and extending lifespan of human mesenchymal stromal cells (MSCs) may enhance their potential for tissue engineering and cell based therapies. Accumulating evidence suggests that inhibitors of the mTOR signaling pathway,… read more here.
Keywords: mesenchymal stromal; replicative senescence; senescence; delaying replicative ... See more keywords