Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline
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DOI: 10.1038/s41586-019-1213-4
Abstract: Mitochondria contain their own genomes that, unlike nuclear genomes, are inherited only in the maternal line. Owing to a high mutation rate and low levels of recombination of mitrochondrial DNA (mtDNA), special selection mechanisms exist… read more here.
Keywords: mtdna; selection; deleterious mtdna; germline ... See more keywords