Articles with "deleterious somatic" as a keyword



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Deleterious somatic variants in 473 consecutive individuals with ovarian cancer: results of the observational AGO-TR1 study (NCT02222883)

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Published in 2019 at "Journal of Medical Genetics"

DOI: 10.1136/jmedgenet-2018-105930

Abstract: Background For individuals with ovarian cancer (OC), therapy options mainly depend on BRCA1/2 germline status. What is the prevalence of deleterious somatic variants, that is, does genetic tumour testing identify subgroups of individuals who also… read more here.

Keywords: predisposition genes; somatic variants; brca1; deleterious somatic ... See more keywords