Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing.
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DOI: 10.1016/j.celrep.2020.107689
Abstract: CRISPR genome editing is a promising tool for translational research but can cause undesired editing outcomes, both on target at the edited locus and off target at other genomic loci. Here, we investigate the occurrence… read more here.
Keywords: target effects; crispr editing; detection deleterious; target ... See more keywords