Articles with "deletion hco3" as a keyword



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Deletion of the Na/HCO3 Transporter NBCn1 Protects Hippocampal Neurons from NMDA-induced Seizures and Neurotoxicity in Mice

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-52413-0

Abstract: The Na/HCO3 cotransporter NBCn1/SLC4A7 can affect glutamate neurotoxicity in primary cultures of rat hippocampal neurons. Here, we examined NMDA-induced neurotoxicity in NBCn1 knockout mice to determine whether a similar effect also occurs in the mouse… read more here.

Keywords: hippocampal neurons; nmda induced; transporter nbcn1; hco3 transporter ... See more keywords