Generation, safety and immunogenicity of an Actinobacillus pleuropneumoniae quintuple deletion mutant SLW07 (ΔapxICΔapxIICΔorf1ΔcpxARΔarcA).
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.02.083
Abstract: We inactivated a virulence determinant, ArcA, in an Actinobacillus pleuropneumoniae quadruple deletion mutant SLW06 (ΔapxICΔapxIICΔorf1ΔcpxAR, serovar 1), and a quintuple deletion mutant SLW07 was generated. SLW07 showed decreased adherence to and invasion of host cells,… read more here.
Keywords: deletion mutant; apxic apxiic; deletion; slw07 ... See more keywords
Integrated Transcriptomic and Proteomic Analyses Reveal the Role of NprR in Bacillus anthracis Extracellular Protease Expression Regulation and Oxidative Stress Responses
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DOI: 10.3389/fmicb.2020.590851
Abstract: NprR is a protein of Bacillus anthracis that exhibits moonlighting functions as either a phosphatase or a neutral protease regulator that belongs to the RNPP family. We previously observed that the extracellular protease activity of… read more here.
Keywords: deletion mutant; nprr deletion; protease; integrated transcriptomic ... See more keywords
The global regulator FpLaeB is required for the regulation of growth, development, and virulence in Fusarium pseudograminearum
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1132507
Abstract: Fusarium pseudograminearum is a soil-borne pathogen that is capable of causing a highly destructive crown disease in wheat. Secondary metabolites (SMs), especially deoxynivalenol (DON), are the primary virulence factors during infection. Here, we characterised the… read more here.
Keywords: fplaeb; deletion mutant; fplaeb deletion; growth ... See more keywords
[Construction of spvD gene deletion mutant and compensation strains in Salmonella enteritidis and its effects on Caco-2 cells].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]"
DOI: 10.3760/cma.j.cn112150-20211120-01073
Abstract: Objective: To analyze the effects of spvD gene on invasion and intracellular proliferation of Caco-2 cells and in order to provide insight into the function of that gene and the underlying mechanism of Salmonella caused… read more here.
Keywords: deletion mutant; caco cells; salmonella enteritidis; compensation ... See more keywords
Direct Monitoring of Membrane Fatty Acid Changes and Effects on the Isoleucine/ Valine Pathways in an ndgR Deletion Mutant of Streptomyces coelicolor.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.2301.01016
Abstract: NdgR, a global regulator in soil-dwelling and antibiotic-producing Streptomyces, is known to regulate branched-chain amino acid metabolism by binding to the upstream region of synthetic genes. However, its numerous and complex roles are not yet… read more here.
Keywords: deletion mutant; deletion; ndgr deletion; valine ... See more keywords