Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis
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DOI: 10.1538/expanim.17-0112
Abstract: Nonalcoholic steatohepatitis (NASH) is one of the leading causes of chronic liver disease worldwide. However, details of pathogenetic mechanisms remain unknown. Deletion of both p62/Sqstm1 and Nrf2 genes spontaneously led to the development of NASH… read more here.
Keywords: nonalcoholic steatohepatitis; p62 nrf2; mice; deletion p62 ... See more keywords