APOBEC3A/B deletion polymorphism and endometrial cancer risk
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DOI: 10.1002/cam4.5448
Abstract: A common 30 kb deletion affecting the APOBEC3A and APOBEC3B genes has been linked to increased APOBEC activity and APOBEC‐related mutational signatures in human cancers. The role of this deletion as a cancer risk factor… read more here.
Keywords: deletion; cancer risk; deletion polymorphism; apobec3a deletion ... See more keywords
Role of angiotensin‐converting enzyme insertion/deletion polymorphism in sudden cardiac arrest
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27622
Abstract: This study aimed to investigate the relationship between angiotensin‐converting enzyme (ACE) insertion/deletion (I/D) polymorphism and to understand sudden cardiac arrest (SCA) in the Chinese population. read more here.
Keywords: sudden cardiac; deletion polymorphism; insertion deletion; converting enzyme ... See more keywords
The angiotensin‐converting enzyme insertion/deletion polymorphism rs4340 associates with habitual physical activity among European American adults
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.308
Abstract: The angiotensin‐converting enzyme (ACE) insertion/deletion (I/D) polymorphism (rs4340) (ACE DIP) accounts for half of the variability in plasma ACE concentrations. ACE has been widely studied for its influence on sports performance; however, research on its… read more here.
Keywords: deletion polymorphism; insertion deletion; converting enzyme; angiotensin converting ... See more keywords
Lack of association between deletion polymorphism of BIM gene and in vitro drug sensitivity in B-cell precursor acute lymphoblastic leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "Leukemia research"
DOI: 10.1016/j.leukres.2017.06.003
Abstract: A deletion polymorphism in the BIM gene was identified as an intrinsic mechanism for resistance to tyrosine kinase inhibitor in chronic myeloid leukemia patients in East Asia. BIM is also involved in the responses to… read more here.
Keywords: polymorphism bim; bim gene; deletion polymorphism; gene ... See more keywords
APOBEC3A/B deletion polymorphism and cancer risk
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DOI: 10.1093/carcin/bgx131
Abstract: The germline ‘APOBEC3A/B’ deletion polymorphism, previously linked to APOBEC-dependent mutational signatures, was found associated with lung cancer risk among young individuals and age at diagnosis for lung and prostate cancer. No associations were found to… read more here.
Keywords: cancer; cancer risk; deletion polymorphism; apobec3a deletion ... See more keywords
The BCL2L11 deletion polymorphism is not associated with imatinib resistance in chronic myeloid leukemia patients: meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21154
Abstract: A common deletion polymorphism of the gene Bcl-2 like protein 11 (BCL2L11, BIM) has been reported to cause tyrosine kinase inhibitors (TKIs) resistance in several malignant tumors. However, the conclusions were not consistent in chronic… read more here.
Keywords: deletion polymorphism; deletion; resistance; chronic myeloid ... See more keywords
The role of angiotensin I converting enzyme insertion/deletion polymorphism in the severity and outcomes of COVID-19 patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1035796
Abstract: The pandemic of coronavirus disease in 2019 has led to a global crisis. COVID-19 shows distinct clinical manifestations of the severity of symptoms. Numerous patients with no associated risk factors demonstrate acute respiratory distress syndrome… read more here.
Keywords: insertion deletion; deletion polymorphism; covid patients; severity ... See more keywords
Association between 19-bp Insertion/Deletion Polymorphism of Dopamine β-Hydroxylase and Autism Spectrum Disorder in Thai Patients
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58091228
Abstract: Background and Objectives: Autism spectrum disorder (ASD) is a neurodevelopmental disorder the cause of which is not fully known. Genetic factors are believed to play a major role in the etiology of ASD. However, genetic… read more here.
Keywords: association insertion; insertion; deletion polymorphism; insertion deletion ... See more keywords