Delineating Physical Organic Parameters in Site-Selective C–H Functionalization of Indoles
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DOI: 10.1021/acscentsci.8b00264
Abstract: Site-selective C–H functionalization is a great challenge in homogeneous transition-metal catalysis. Herein, we present a physical organic approach to delineate the origin of regioselective amidation of N-acylindoles through Ir(III) catalysis. Bulkiness of N-directing groups of… read more here.
Keywords: selective functionalization; site selective; physical organic; delineating physical ... See more keywords