Development and Validation of an Electronic Health Record–Based Machine Learning Model to Estimate Delirium Risk in Newly Hospitalized Patients Without Known Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2018.1018
Abstract: Key Points Question Can machine learning be used to predict incident delirium in newly hospitalized patients using only data available in the electronic health record shortly after admission? Findings In this cohort study, classification models… read more here.
Keywords: machine; machine learning; electronic health; health record ... See more keywords
Suvorexant for Reduction of Delirium in Older Adults After Hospitalization
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.27691
Abstract: Key Points Question Does suvorexant, a sleep-promoting orexin receptor antagonist, reduce delirium in older adults at high risk for delirium after hospitalization? Findings In this randomized clinical trial of 203 participants, 17% in the suvorexant-treated… read more here.
Keywords: suvorexant reduction; reduction delirium; delirium; delirium older ... See more keywords
Validation of 4 Risk Stratification Tools for Delirium in the Emergency Department
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.40920
Abstract: Key Points Question Are previously developed delirium risk stratification tools applicable to a different setting in the emergency department (ED)? Findings In this prognostic study including 44 578 patients, 3 of the 4 delirium scores demonstrated… read more here.
Keywords: delirium; delirium emergency; emergency; stratification tools ... See more keywords
Machine Learning Multimodal Model for Delirium Risk Stratification
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.8874
Abstract: Key Points Question Can a machine learning model be used to accurately stratify risk of hospital delirium in live clinical practice? Findings This quality improvement study including 32 284 inpatient admissions developed an automated multimodal machine… read more here.
Keywords: delirium; delirium risk; model; machine learning ... See more keywords
Effect of Cognitive Prehabilitation on the Incidence of Postoperative Delirium Among Older Adults Undergoing Major Noncardiac Surgery: The Neurobics Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA surgery"
DOI: 10.1001/jamasurg.2020.4371
Abstract: Importance Postoperative delirium in older adults is a common and costly complication after surgery. Cognitive reserve affects the risk of postoperative delirium, and thus preoperative augmentation of reserve as a preventive technique is of vital… read more here.
Keywords: intervention; surgery; trial; older adults ... See more keywords
Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70029
Abstract: Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction… read more here.
Keywords: disease model; delirium; development disease; postoperative delirium ... See more keywords
Circadian Rest–Activity Rhythms, Delirium Risk, and Progression to Dementia
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26617
Abstract: Delirium is a complex neurocognitive syndrome suspected to be bidirectionally linked to dementia. Circadian rhythm disturbances likely contribute to dementia pathogenesis, but whether these disturbances are related to delirium risk and progression to all‐cause dementia… read more here.
Keywords: risk progression; delirium risk; delirium; dementia ... See more keywords
Identification of risk factors for postoperative delirium in elderly patients with hip fractures by a risk stratification index model: A retrospective study.
Sign Up to like & getrecommendations! Published in 2021 at "Brain and behavior"
DOI: 10.1002/brb3.2420
Abstract: INTRODUCTION Postoperative delirium is one of the most common and dangerous psychiatric complications after hip surgery. The aim of this study was to investigate the incidence of postoperative delirium in elderly patients after hip fracture… read more here.
Keywords: hip; risk factors; elderly patients; delirium ... See more keywords
Identifying hormones and other perioperative risk factors for postoperative delirium after endoscope-assisted transsphenoidal pituitary adenoma resection: A retrospective, matched cohort study.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3041
Abstract: OBJECTIVE As a complex and acute brain dysfunction, if postoperative delirium (POD) occurs in the postoperative period, it will lead to a prolonged length of stay in the critical care unit, with increased hospitalization costs… read more here.
Keywords: pituitary adenoma; assisted transsphenoidal; delirium; resection ... See more keywords
Plasma SOMAmer proteomics of postoperative delirium
Sign Up to like & getrecommendations! Published in 2024 at "Brain and Behavior"
DOI: 10.1002/brb3.3422
Abstract: Postoperative delirium is prevalent in older adults and has been shown to increase the risk of long‐term cognitive decline. Plasma biomarkers to identify the risk for postoperative delirium and the risk of Alzheimer's disease and… read more here.
Keywords: plasma somamer; delirium; proteomics postoperative; risk ... See more keywords
Medication Causes and Treatment of Delirium in Patients With and Without Dementia
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70706
Abstract: Medication associated with delirium in adult patients is poorly understood and considered both a predisposing and precipitating factor. Prescribing advice is lacking. This systematic review aims to collate evidence on medication risks in delirium associated… read more here.
Keywords: treatment; without dementia; delirium; medication ... See more keywords