Constrained Nanoparticles Deliver siRNA and sgRNA to T Cells In Vivo without Targeting Ligands.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201902251
Abstract: T cells help regulate immunity, which makes them an important target for RNA therapies. While nanoparticles carrying RNA have been directed to T cells in vivo using protein- and aptamer-based targeting ligands, systemic delivery to… read more here.
Keywords: without targeting; cells vivo; sirna sgrna; deliver sirna ... See more keywords
Lipopeptide Delivery of siRNA to the Central Nervous System.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9092-4_26
Abstract: RNA interference is a relatively new tool used to silence specific genes in diverse biological systems. The development of this promising new technique for research and therapeutic use in studying and treating neurological diseases has… read more here.
Keywords: nervous system; central nervous; deliver sirna; lipopeptide delivery ... See more keywords