Translational Approaches for Brain Delivery of Biologics via Cerebrospinal Fluid
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.2531
Abstract: Delivery of biologics via cerebrospinal fluid (CSF) has demonstrated potential to access the tissues of the central nervous system (CNS) by circumventing the blood‐brain barrier and blood‐CSF barrier. Developing an effective CSF drug delivery strategy… read more here.
Keywords: delivery biologics; via cerebrospinal; brain; cerebrospinal fluid ... See more keywords
Hydrogels for sustained delivery of biologics to the back of the eye.
Sign Up to like & getrecommendations! Published in 2019 at "Drug discovery today"
DOI: 10.1016/j.drudis.2019.05.037
Abstract: Hydrogels are water-laden polymer networks that have been used for myriad biological applications. By controlling the chemistry through which a hydrogel is constructed, a wide range of chemical and physical properties can be accessed, making… read more here.
Keywords: delivery; chemistry; delivery biologics; biologics back ... See more keywords
Flame-Made Calcium Phosphate Nanoparticles with High Drug Loading for Delivery of Biologics
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25071747
Abstract: Nanoparticles exhibit potential as drug carriers in biomedicine due to their high surface-to-volume ratio that allows for facile drug loading. Nanosized drug delivery systems have been proposed for the delivery of biologics facilitating their transport… read more here.
Keywords: drug loading; calcium phosphate; delivery; delivery biologics ... See more keywords
Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11030127
Abstract: Biologics have changed the management of Inflammatory Bowel Disease (IBD), but there are concerns regarding unexpected systemic toxicity and loss of therapeutic response following administration by injection. Local delivery of biologics directly to the inflamed… read more here.
Keywords: hydrogel; bsa; delivery; delivery biologics ... See more keywords
Oral Delivery of Biologics via the Intestine
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13010018
Abstract: Biologics are currently one of the most promising avenues for therapeutic interventions in conditions such as metabolic disease, ageing and inflammatory disorders, and for chronic ailments, oral delivery of such medicines has for years been… read more here.
Keywords: oral delivery; delivery; delivery biologics; biologics via ... See more keywords