Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical research"
DOI: 10.1007/s11095-022-03241-x
Abstract: Limited drug delivery to the brain is one of the major reasons for high failure rates of central nervous system (CNS) drug candidates. The blood-brain barrier (BBB) with its tight junctions, membrane transporters, receptors and… read more here.
Keywords: drug delivery; delivery; delivery brain; targeting transporters ... See more keywords
eBrain: a Three Dimensional Simulation Tool to Study Drug Delivery in the Brain
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-42261-3
Abstract: Neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease are severe disorders with acute symptoms that gradually progress. In the course of developing disease-modifying treatments for neurodegenerative disorders there is a need to develop novel strategies… read more here.
Keywords: drug; drug delivery; tool; delivery brain ... See more keywords
Miniaturized Neural Implants for Localized and Controllable Drug Delivery in Brain
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Materials Chemistry B"
DOI: 10.1039/d3tb00728f
Abstract: Drug delivery in brain has been challenging due to the existence of blood brain barrier, which prevents most drugs from entering the target site in brain. Compared to systematic drug... read more here.
Keywords: delivery brain; brain; drug delivery; drug ... See more keywords
Functionalized liposomes for intranasal levodopa delivery to the brain
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2025.2509273
Abstract: Abstract Objective The study evaluated functionalized liposomes as potential carriers for intranasal delivery of levodopa. Methods Lipid film hydration method was used to obtain conventional and functionalized liposomes with polyethylene glycol or maleimide-PEG. The liposome… read more here.
Keywords: delivery; levodopa delivery; intranasal levodopa; delivery brain ... See more keywords
Book Review: Drug Delivery to the Brain-Physiological Concepts, Methodologies and Approaches.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug delivery"
DOI: 10.2174/1567201814999170314115103
Abstract: By reading, you can know the knowledge and things more, not only about what you get from people to people. Book will be more trusted. As this drug delivery to the brain physiological concepts methodologies… read more here.
Keywords: brain physiological; drug delivery; physiological concepts; drug ... See more keywords
Nanocarrier based Drug Delivery to Brain: Interventions of Surface Modification.
Sign Up to like & getrecommendations! Published in 2022 at "Current neuropharmacology"
DOI: 10.2174/1570159x20666220706121412
Abstract: Brain disorders are one of the prevalent and rapidly growing problems in the medical field as they adversely affect the quality of life of a human. With increase in life expectancy, it has been reported… read more here.
Keywords: delivery brain; brain; drug delivery; based drug ... See more keywords
Exploiting Focused Ultrasound to Aid Intranasal Drug Delivery for Brain Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.786475
Abstract: Novel effective therapeutic strategies are needed to treat brain neurodegenerative diseases and to improve the quality of life of patients affected by Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), Amyotrophic Lateral sclerosis (ALS)… read more here.
Keywords: focused ultrasound; delivery brain; brain; drug delivery ... See more keywords
An Overview of Nanotechnologies for Drug Delivery to the Brain
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14020224
Abstract: Drug delivery to the brain has been one of the toughest challenges researchers have faced to develop effective treatments for brain diseases. Owing to the blood–brain barrier (BBB), only a small portion of administered drug… read more here.
Keywords: drug; delivery brain; drug delivery; overview nanotechnologies ... See more keywords
Implantable systems for drug delivery to the brain.
Sign Up to like & getrecommendations! Published in 2017 at "Therapeutic delivery"
DOI: 10.4155/tde-2017-0082
Abstract: Most diseases and disorders of the brain require long-term therapy and a constant supply of drugs. Implantable drug-delivery systems provide long-term, sustained drug delivery in the brain. The present review discusses different type of implantable… read more here.
Keywords: drug delivery; delivery; delivery brain; implantable systems ... See more keywords