Direct Intracellular Delivery of Cell‐Impermeable Probes of Protein Glycosylation by Using Nanostraws
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201600689
Abstract: Bioorthogonal chemistry is an effective tool for elucidating metabolic pathways and measuring cellular activity, yet its use is currently limited by the difficulty of getting probes past the cell membrane and into the cytoplasm, especially… read more here.
Keywords: delivery; direct intracellular; glycosylation; delivery cell ... See more keywords
Preclinical development of an automated injection device for intradermal delivery of a cell-based therapy
Sign Up to like & getrecommendations! Published in 2017 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-017-0418-z
Abstract: Current methods for intradermal delivery of therapeutic products in clinical use include manual injection via the Mantoux technique and the use of injection devices, primarily developed for the delivery of vaccines and small molecules. A… read more here.
Keywords: delivery; intradermal delivery; delivery cell; injection ... See more keywords
Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo.
Sign Up to like & getrecommendations! Published in 2018 at "Nano letters"
DOI: 10.1021/acs.nanolett.8b03149
Abstract: Nanoparticles are often targeted to receptors expressed on specific cells, but few receptors are (i) highly expressed on one cell type and (ii) involved in endocytosis. One unexplored alternative is manipulating an endocytic gene expressed… read more here.
Keywords: delivery; delivery cell; commonly expressed; cell ... See more keywords
Enhanced Drug Delivery into Cell Cytosol via Glycoprotein H-Derived Peptide Conjugated Nanoemulsions.
Sign Up to like & getrecommendations! Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.7b03058
Abstract: The key role of nanocarriers in improving the pharmacological properties of commonly used drugs is recognized worldwide. It is also known that in the development of new effective nanocarriers the use of targeting moieties integrated… read more here.
Keywords: cytosol via; drug delivery; cell cytosol; enhanced drug ... See more keywords
Cell-Penetrating Peptides: A Powerful Tool for Targeted Drug Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Current drug delivery"
DOI: 10.2174/1567201820666230407092924
Abstract: The cellular membrane hinders the effective delivery of therapeutics to targeted sites. Cellpenetrating peptide (CPP) is one of the best options for rapidly internalizing across the cellular membrane. CPPs have recently attracted lots of attention… read more here.
Keywords: delivery cell; cell penetrating; penetrating peptides; drug delivery ... See more keywords