The Delivery Challenge of Genome Editing in Human Epithelia.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202100847
Abstract: Despite exciting advances in gene editing, their clinical translation is still hampered by the lack of delivery systems that can encapsulate and deliver gene editing tools like CRISPR-Cas9 or prime editors to the target side.… read more here.
Keywords: genome editing; gene editing; human epithelia; delivery ... See more keywords
The delivery challenge: fulfilling the promise of therapeutic genome editing
Sign Up to like & getrecommendations! Published in 2020 at "Nature Biotechnology"
DOI: 10.1038/s41587-020-0565-5
Abstract: Genome editing has the potential to treat an extensive range of incurable monogenic and complex diseases. In particular, advances in sequence-specific nuclease technologies have dramatically accelerated the development of therapeutic genome editing strategies that are… read more here.
Keywords: challenge fulfilling; genome editing; delivery challenge; genome ... See more keywords