Flattening filter free in intensity‐modulated radiotherapy (IMRT) – Theoretical modeling with delivery efficiency analysis
Sign Up to like & getrecommendations! Published in 2019 at "Medical Physics"
DOI: 10.1002/mp.13267
Abstract: PURPOSE The flattening filter (FF) has traditionally been used to flatten beams or create uniform fields in conformal and intensity-modulated radiation therapy (IMRT) but reduces the dose rate. Many studies have confirmed improvement in delivery… read more here.
Keywords: fff beam; field; delivery efficiency; beam ... See more keywords
Self-Disguised Nanospy for Improving Drug Delivery Efficiency via Decreasing.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202300060
Abstract: Nanoscale drug carriers play a crucial role in reducing side effects of chemotherapy drugs. However, the mononuclear phagocyte system (MPS) and the drug protonation after nanoparticles (NPs) burst release still limit the drug delivery efficiency.… read more here.
Keywords: disguised nanospy; delivery efficiency; self disguised; drug delivery ... See more keywords
A theoretical study of the parameters affecting the power delivery efficiency of an agricultural tractor
Sign Up to like & getrecommendations! Published in 2019 at "Biosystems Engineering"
DOI: 10.1016/j.biosystemseng.2019.07.006
Abstract: Tractive efficiency is of major concern to agricultural tractors manufacturers, end-users and to society as well, both for economical and environmental reasons. In this article, a traction model of a whole vehicle is developed which… read more here.
Keywords: tractor; efficiency; delivery efficiency; power delivery ... See more keywords
Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach
Sign Up to like & getrecommendations! Published in 2020 at "ACS Nano"
DOI: 10.1021/acsnano.9b08142
Abstract: Numerous studies have engineered nanoparticles with different physicochemical properties to enhance the delivery efficiency to solid tumors, yet the mean and median delivery efficiencies are only 1.48% and 0.70% of the injected dose (%ID), respectively,… read more here.
Keywords: modeling simulation; based pharmacokinetic; delivery; physiologically based ... See more keywords
Spatial Conformation of Ionizable Lipids Regulates Endosomal Membrane Disruption.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c10908
Abstract: The delivery efficiency of biologics via lipid nanoparticles (LNPs) is critically dependent on the incorporation of ionizable lipids. The subtle structural changes to these lipids led to dramatic variations in cytosolic delivery efficiency. However, beyond… read more here.
Keywords: membrane disruption; disruption; delivery efficiency; ionizable lipids ... See more keywords
The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency
Sign Up to like & getrecommendations! Published in 2019 at "Nature Biomedical Engineering"
DOI: 10.1038/s41551-019-0405-4
Abstract: Extracellular microparticles (MPs) can function as drug-delivery vehicles for anticancer drugs. Here, we show that the softness of MPs derived from tumour-repopulating cells (TRCs) isolated from three-dimensional fibrin gels enhances the MPs’ drug-delivery efficiency. We… read more here.
Keywords: drug delivery; delivery; efficiency; delivery efficiency ... See more keywords
On the Content Delivery Efficiency of NOMA Assisted Vehicular Communication Networks With Delay Constraints
Sign Up to like & getrecommendations! Published in 2020 at "IEEE Wireless Communications Letters"
DOI: 10.1109/lwc.2020.2973138
Abstract: In this letter, we focus on the content delivery efficiency in vehicular communication networks (VCNs), where the content delivery can share the same channel resource with the safety message transmission by adopting non-orthogonal multiple access… read more here.
Keywords: content delivery; vehicular communication; delivery; delivery efficiency ... See more keywords
Does the Locker Alliance Network Improve Last Mile Delivery Efficiency?
Sign Up to like & getrecommendations! Published in 2025 at "Management Science"
DOI: 10.1287/mnsc.2024.04567
Abstract: The Locker Alliance Network (LAN), a cutting-edge initiative under Singapore’s Smart Nation vision, aims to revolutionize parcel pickup processes. This government-led project seeks to implement two major changes in Singapore’s urban logistics: (i) establishing an… read more here.
Keywords: delivery efficiency; delivery; locker; network ... See more keywords
In vivo, in situ and ex vivo comparison of porcine skin for microprojection array penetration depth, delivery efficiency and elastic modulus assessment.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.2139/ssrn.3998970
Abstract: With the development of wearable technologies, the interfacial properties of skin and devices have become much more important. For research and development purposes, porcine skin is often used to evaluate device performance, but the differences… read more here.
Keywords: delivery efficiency; penetration depth; vivo;
In Silico Study to Enhance Delivery Efficiency of Charged Nanoscale Nasal Spray Aerosols to the Olfactory Region Using External Magnetic Fields
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9010040
Abstract: Various factors and challenges are involved in efficiently delivering drugs using nasal sprays to the olfactory region to treat central nervous system diseases. In this study, computational fluid dynamics was used to simulate nasal drug… read more here.
Keywords: olfactory region; delivery; delivery efficiency; efficiency ... See more keywords
State of the Art in Constructing Gas-Propelled Dissolving Microneedles for Significantly Enhanced Drug-Loading and Delivery Efficiency
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15041059
Abstract: Dissolving microneedles (MNs) have emerged as a promising transdermal delivery system, as they integrate the advantages of both injection and transdermal preparations. However, the low drug-loading and limited transdermal delivery efficiency of MNs severely hinder… read more here.
Keywords: drug loading; drug; gas propelled; delivery efficiency ... See more keywords