Functional siRNA Delivery by Extracellular Vesicle-Liposome Hybrid Nanoparticles.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101202
Abstract: The therapeutic use of RNA interference is limited by the inability of siRNA molecules to reach their site of action, the cytosol of target cells. Lipid nanoparticles, including liposomes, are commonly employed as siRNA carrier… read more here.
Keywords: functional sirna; sirna delivery; delivery extracellular; delivery ... See more keywords
The Delivery of Extracellular “Danger” Signals to Cytosolic Sensors in Phagocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.944142
Abstract: Phagocytes, such as macrophages and dendritic cells, possess the ability to ingest large quantities of exogenous material into membrane-bound endocytic organelles such as macropinosomes and phagosomes. Typically, the ingested material, which consists of diverse macromolecules… read more here.
Keywords: endocytic organelles; delivery extracellular; macromolecular danger; danger signals ... See more keywords