The exogenous delivery of microRNA-449b-5p using spermidine-PLGA nanoparticles efficiently decreases hepatic injury
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra06129k
Abstract: The present study highlights the importance of miR-449b-5p in the inhibition of HMGB1 and thereby it's treatment potential in hepatic injury. read more here.
Keywords: exogenous delivery; microrna 449b; delivery microrna; 449b using ... See more keywords
Endocrine Delivery of MicroRNA-210: A Trusted Traveler That Mediates Pulmonary Hypertension.
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DOI: 10.1161/circresaha.120.317625
Abstract: M icroRNAs (miRNAs) have emerged as key determinants of health and disease by mediating gene expression in response to homeostatic or pathogenic stimuli. Considerable advances in miRNA biology have revealed that many miRNAs are expressed… read more here.
Keywords: microrna 210; endocrine delivery; disease; delivery microrna ... See more keywords
Systemic delivery of MicroRNA mimics with polyethylenimine elevates pulmonary microRNA levels, but lacks pulmonary selectivity
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DOI: 10.1177/2045893217750613
Abstract: Reversing pathologic alterations in vascular microRNA (miRNA) expression represents a potential therapeutic strategy for pulmonary hypertension. While polyethylenimine (PEI) has previously been shown to be an effective vehicle for vascular lung-directed delivery of plasmid DNA,… read more here.
Keywords: mimics polyethylenimine; microrna mimics; delivery; delivery microrna ... See more keywords