Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation.
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DOI: 10.1016/j.actbio.2020.03.045
Abstract: Application of messenger RNA (mRNA) for bone regeneration is a promising alternative to DNA, recombinant proteins and peptides. However, exogenous in vitro transcribed mRNA (IVT mRNA) triggers innate immune response resulting in mRNA degradation and… read more here.
Keywords: expression; murine pluripotent; delivery ns1; ns1 ... See more keywords