Nanotechnology‐Assisted RNA Delivery: From Nucleic Acid Therapeutics to COVID‐19 Vaccines
Sign Up to like & getrecommendations! Published in 2021 at "Small Methods"
DOI: 10.1002/smtd.202100402
Abstract: Abstract In recent years, the main quest of science has been the pioneering of the groundbreaking biomedical strategies needed for achieving a personalized medicine. Ribonucleic acids (RNAs) are outstanding bioactive macromolecules identified as pivotal actors… read more here.
Keywords: rna delivery; nanotechnology assisted; nanotechnology; assisted rna ... See more keywords
Transdermal Delivery of Nucleic Acid Mediated by Punching and Electroporation.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9740-4_11
Abstract: Transdermal delivery of gene medicine holds a great promise in gene therapy, and electroporation-mediated method is a high-efficiency drug transfer technique. Traditional skin electroporation approaches require high voltage that may cause severe injure. In this… read more here.
Keywords: transdermal delivery; nucleic acid; delivery; electroporation ... See more keywords
Liver-targeted delivery of nucleic acid by liposomes modified with a glycoconjugate
Sign Up to like & getrecommendations! Published in 2017 at "Mendeleev Communications"
DOI: 10.1016/j.mencom.2017.11.030
Abstract: A drug delivery system based on liposomes has been modified by targeted vectors based on a glycoconjugate, and the vector structure has been optimized. The glycoconjugate in liposomes almost fourfold increases the transfection efficiency of… read more here.
Keywords: liver targeted; delivery; liposomes modified; targeted delivery ... See more keywords
Therapeutic delivery of nucleic acids for skin wound healing.
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic delivery"
DOI: 10.4155/tde-2022-0003
Abstract: Though wound care has advanced, treating chronic wounds remains a challenge and there are many clinical issues that must be addressed. Gene therapy is a recent approach to treating chronic wounds that remains in its… read more here.
Keywords: therapeutic delivery; nucleic acids; delivery nucleic; chronic wounds ... See more keywords
Advances in the polymeric delivery of nucleic acid vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.70853
Abstract: Nucleic acid vaccines, especially messenger RNA (mRNA) vaccines, display unique benefits in the current COVID-19 pandemic. The application of polymeric materials as delivery carriers has greatly promoted nucleic acid vaccine as a promising prophylactic and… read more here.
Keywords: acid vaccines; polymeric delivery; delivery nucleic; nucleic acid ... See more keywords